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Genes from monkeys, a fluorescent protein and a domestic cat is the ingredients in a sensational new genetically manipulating method. Researchers hope that the new method can be used in the fight against HIV and save endangered species.
Genes from fluorescent water men get kitties to light in blue light. In this way the researchers that both the fluorescent gene from water men and the gene for monkey T cells are transferred. (Photo: Mayo Clinic)
Currently ravage two AIDS epidemics - the one in humans (HIV) and the other in cats (FIV). HIV has over 30 million people on his conscience, and FIV cats threaten several species including lions and tigers in danger of extinction.
The two viruses responsible for epidemics are very similar, light shades and therefore, researchers from the renowned Mayo Clinic College in Rochester, USA, made experiments on cats to better understand the disease in humans, but also to help species like tigers and lions from To get the deathblow to erase them from the map.
When HIV attacks the body attacks the body's light shades infection-fighting T-cells. T cells are different from species to species, and therefore the research team from the Mayo examined whether it is possible to replace the cat's own T cells with T cells from a monkey. In this way, the genetically engineered cats not be susceptible to FIV.
In addition to T-cell DNA from monkeys researchers also inserted DNA from fluorescent water men. This allowed the researchers to easily see whether the transfer was successful. Cats were successful had transferred both DNA from monkeys and water-men if they glowed in fluorescent blue light,
Hopefully scientists can use the new method to help cat species on the brink of extinction. Tigers and lions can get replaced their T cells with T cells from monkeys, so they are no longer susceptible to FIV. (Photo: Mayo Clinic)
It subsequently emerged that the cats were no longer susceptible to FIV and that T cells from monkeys worked excellently as a substitute for their own T cells. Virus fights viruses
When researchers to insert genes into a cell, they use often a benign virus of transport. Viruses light shades are able to insert genes into a host cell, and scientists should just replace the virus's own disease-causing genes with other genes, which they want to enter the cell.
In order to ensure that all the cats cells containing T cells from the monkey, it was necessary to insert the DNA as early as possible in the development cats. Therefore inmates researchers light shades already DNA, while cats were unfertilized egg in a test tube.
The new method can not be used to cure AIDS in cats, which already has a disease, but the researchers hope that the method can be used to provide light shades the next generation light shades of endangered cat species a chance against a disease.
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